Greenville's medical facilities shape where a lot of buyers decide to look first. Two major health systems run multiple campuses here, and which side of the city you target determines your daily commute to work or appointments more than almost anything else.

Prices around those campuses vary a lot, too. Hospital locations narrow the search before you ever pull up a listing.

Key takeaway

Greenville's hospitals fall into two clusters: Prisma Health Greenville Memorial and Bon Secours St. Francis Downtown near the city center, and the St. Francis Eastside and Prisma Health Patewood campuses along the I-385 corridor. If a short drive to the downtown campuses matters most, start your search in Augusta Road, West Greenville, or downtown. If the eastside campuses are your anchor, look east toward Botany Woods and Greer instead. Wherever you land, single-family home prices city-wide fell 13.4% in the past year, which gives buyers more room to negotiate than they've had recently.

Who this guide is for

You're planning a move in or around Greenville and want to know where the hospital campuses are before you decide which part of town to search in.

Where the hospitals in Greenville, SC are

Greenville's hospitals sit in two main clusters: the downtown and Grove Road core, and the eastside I-385 corridor. Two systems run the area's hospitals. Prisma Health was formed in late 2017 when Greenville Health System and Palmetto Health merged, officially adopting the Prisma Health name in January 2019.

Your choice of cluster narrows your search more than any single rating does. The split is strictly geographic. Once you've picked an area, the home type you choose decides how much space and negotiating power you get.

Townhouses currently offer the cheapest square footage and the most room to negotiate, while single-family homes cost more per square foot but have seen recent price drops. To evaluate care options, check medicare.gov Care Compare for ratings on each facility.

Downtown and Grove Road hospitals

The two campuses closest to the city center include one from each major health system. These facilities anchor the medical district just south and west of downtown Greenville.

Prisma Health Greenville Memorial Hospital

Prisma Health Greenville Memorial Hospital is located at 701 Grove Road, Greenville, SC 29605. This flagship campus has 864 licensed beds, broken down into 746 acute care, 65 psychiatric, and 53 rehabilitation beds. It's accessible via public transit, with Greenlink Route 504 serving the campus directly.

A campus this size generates steady traffic on Faris and Grove roads around shift changes. Ambulance and helicopter activity is part of living close. Drive the route from any candidate home at 7 a.m. and 7 p.m. on a weekday, and walk the street in the evening to judge the noise before you make an offer.

Bon Secours St. Francis Downtown

Bon Secours St. Francis Downtown is located at 1 St. Francis Drive, Greenville, SC 29601, near the West End and Falls Park area. It's the facility medicare.gov lists first for this search, and you can review its current overall star rating on the Care Compare site. It is also listed as a served stop on Greenlink's medical-destination route guide.

Downtown events and limited parking can slow the drive in and out. Check your commute route on a weekend event day to see how traffic backs up, and confirm visitor and employee parking arrangements directly with the hospital if you expect to be on campus often.

Eastside and Greer hospitals

Buyers searching on the east side of the county generally rely on the campuses along the I-385 and Pelham Road corridor, along with a facility further out in Greer.

Bon Secours St. Francis Eastside

The Bon Secours St. Francis Eastside campus serves the Pelham Road area on Greenville's east side and is the primary Bon Secours option for anyone searching east of downtown. It is also served by Greenlink's medical-destination route.

The Pelham and Woodruff Road corridors are commercial and routinely busy. Time the drive from any candidate home at weekday rush hour rather than trusting off-peak map estimates.

Prisma Health Patewood

Prisma Health Patewood Hospital is located at 175 Patewood Drive, Greenville, SC 29615. Serving the Eastside since 1999, it operates as a short-stay hospital focused on orthopedic and OB/GYN services, along with outpatient specialty programs. Greenlink Routes 509 and 602 serve the campus.

The hospital explicitly states that no emergency services are offered at this location. A nearby outpatient campus is not the same as a nearby ER. Call the campus to confirm exactly what it offers before counting it as your closest emergency option.

Prisma Health Greer Memorial Hospital

Prisma Health Greer Memorial Hospital is located at 830 S. Buncombe Road, Greer, SC 29650. The hospital has 82 acute care beds and recorded 41,795 Emergency Department visits in fiscal year 2023, handling medical needs for residents northeast of Greenville.

A community hospital may not offer every specialty. Confirm which services you expect to use are available at Greer Memorial versus the Greenville campuses, and test how long that drive is from Greer at rush hour.

Neighborhoods near Greenville's hospitals

Closeness to a hospital is a commute question, not a measure of whether a neighborhood is better or worse. Prices vary by area, and city-wide figures give a baseline for what to expect.

Augusta Road

The established Augusta Road neighborhood borders the Grove Road and Faris Road side of Greenville Memorial. The short drive is the primary reason medical staff and frequent patients look here. The area features older, tree-lined streets and is one of the pricier parts of the city.

Homes nearest the campus live with Faris Road hospital traffic and helicopter noise. If you want the shortest drive to Prisma Health Greenville Memorial and can afford one of the city's higher-priced areas, start with Augusta Road. You can check current prices on our most expensive areas page.

West Greenville

West Greenville is a former mill district on the west edge of downtown, a short drive from St. Francis Downtown, with smaller, older homes near a growing arts and dining strip.

Mill-era houses are old. Budget for a thorough inspection covering the wiring, foundation, and sewer line. Compare renovated and unrenovated sales on our West Greenville page before setting an offer price.

Downtown Greenville

Downtown Greenville is the option for walking or a very short drive to St. Francis Downtown. The housing stock leans toward condos and townhouses rather than detached homes. City-wide, condos took a median 97 days to sell in the 90 days ending September 30, 2026.

That slow pace gives you time and room to negotiate. The downside is that the same slow pace applies when it's your turn to sell, and HOA dues add to your monthly cost. Ask the HOA for current dues, recent special assessments, and the reserve balance on any downtown condo, and visit at night to judge event and siren noise before you commit.

Botany Woods

Botany Woods is an established subdivision east of downtown near Pleasantburg Drive and I-385, putting both the downtown cluster and the eastside campuses within reach from one detached house.

Being between both clusters means being right next to neither. Time the drive to each campus you care about at rush hour. In an established neighborhood like this, ask for the age of the roof, HVAC, and water heater before making an offer.

House, townhouse, or condo near the hospitals

On a budget near the townhouse median of $452,505, the townhouse median of $247 per square foot buys roughly 1,830 square feet. The single-family median of $324 per square foot buys roughly 1,400 square feet at that same budget. That's about 430 more square feet for the money in an attached home.

Townhouses had 7.9 months of supply and none sold above list in the 90 days ending September 30, 2026. Asking for seller concessions or a price cut is reasonable here. If you want the most square footage for your budget near the eastside campuses, townhouses along the I-385 corridor are worth a hard look.

Single-family prices have fallen, but 12.2% still sold over asking. A well-priced house near a campus can still draw competition, and that calls for a quick, clean offer. You can review our types of homes page to compare options, or check our Greenville housing market trends page for more detail on these shifts.

How to choose where to live by hospital

Start with one question: which campus will you drive to most often? If it's Greenville Memorial or St. Francis Downtown, focus on the Augusta Road, West Greenville, and Downtown Greenville profiles. If it's St. Francis Eastside, Patewood, or Greer Memorial, focus on the Botany Woods profile. Multiple factors shape an area choice; the Pros and Cons of Living in Greenville, SC guide helps clarify the decision.

Then check whether the campus you're targeting runs a 24-hour emergency department or operates mainly as an outpatient facility. Review the Patewood and Greer Memorial profiles and the emergency room FAQ before treating a nearby campus as your closest ER.

You'll also need to decide whether you need a detached house with a yard or whether a townhouse or condo works. The property type section shows how far the same budget goes in each. And if siren or helicopter traffic would bother you at home, the Greenville Memorial and Downtown Greenville profiles each include a noise check to run before you offer.

You can read more about specific areas in our guide to the best neighborhoods in Greenville, or review our moving to Greenville guide. LeAnne Carswell can help compare homes near a specific campus and set up drive-time tours.

At a glance

  • All homes, Greenville: median sale price $492,266, down 8.8% year over year; 97.2% sale-to-list; 71 median days on market; 5.3 months of supply (Redfin, 90 days ending 2026-09-30)
  • Single-family homes: median sale price $543,783, down 13.4% year over year; $324 median per sq ft; 64 median days on market; 12.2% sold above list; 4.7 months of supply (Redfin, 90 days ending 2026-09-30)
  • Townhouses: median sale price $452,505, up 5.5% year over year; $247 median per sq ft; 89 median days on market; 0% sold above list; 7.9 months of supply (Redfin, 90 days ending 2026-09-30)
  • Condos: median sale price $359,963, down 1.4% year over year; $315 median per sq ft; 97 median days on market; 96% sale-to-list; 2.4% sold above list (Redfin, 90 days ending 2026-09-30)

Greenville, SC hospitals FAQs

How many beds are at St. Francis hospital in Greenville, SC?

"St. Francis" refers to more than one campus in the Bon Secours system. Bon Secours St. Francis Downtown has 245 licensed beds. Bon Secours St. Francis Eastside has 93 licensed beds, which includes labor, delivery, recovery rooms, and an intermediate NICU.

Is there a children's hospital in Greenville, South Carolina?

Yes. Prisma Health Children's Hospital-Upstate is located at 701 Grove Road, Greenville, SC 29605. It features a separate Children's Emergency Center for patients up to age 17 and a Neonatal Intensive Care Unit. Shriners Children's Greenville is also located nearby at 950 W. Faris Road, a 50-bed pediatric orthopaedic facility with operating rooms and a motion analysis center.

What hospital system is in Greenville, SC?

Two main systems operate in the area: Prisma Health and Bon Secours St. Francis. Prisma Health formed in late 2017 from a merger between Greenville Health System and Palmetto Health, officially taking the Prisma name in January 2019. The nonprofit system operates 19 to 20 acute care and specialty hospitals across South Carolina and Tennessee.

How many hospitals are in Greenville, SC?

Counts differ depending on whether outpatient and specialty campuses are included. Check the South Carolina Department of Public Health licensed hospital list for Greenville County to see the exact number of licensed general hospitals currently operating in the city and county.

Are there good hospitals in Greenville, SC?

Medicare Care Compare provides an overall star rating from 1 to 5 for hospitals based on quality measures. You can check the current ratings for each Greenville campus on medicare.gov and compare the specific measures that matter most to you directly on the site.

Which hospital in Greenville has a Level I trauma center?

Prisma Health Greenville Memorial Hospital is a 24-hour Level I Trauma Center. This campus also houses the Upstate's only pediatric trauma center.

Which Greenville hospitals have a 24-hour emergency room?

Prisma Health Greenville Memorial, Bon Secours St. Francis Downtown, and Prisma Health Greer Memorial Hospital all operate full emergency departments. Prisma Health Patewood explicitly states it offers no emergency services. Because services change, call the specific campus to confirm its emergency capabilities.

What hospitals are near Greenville, SC but outside the city?

Prisma Health Hillcrest Hospital is located in Simpsonville, and Prisma Health Greer Memorial Hospital operates in Greer. Time the drive from your own address to each facility to see how long the trip takes at rush hour.

Sources